Lutetium-177 PSMA Therapy

Get the best Lutetium-177 PSMA Therapy in India at an affordable cost at World Class Cancer Hospitals in India.


Lutetium-177 PSMA therapy is a new, cutting-edge treatment for prostate cancer that is showing great promise. This therapy uses a radioactive isotope called lutetium-177, which targets and kills cancer cells while sparing healthy tissue. Lutetium-177 PSMA therapy is currently being used in clinical trials and has been shown to be effective in treating prostate cancer. This treatment is non-invasive just like Actinium (Ac225) PSMA Therapy and has very few side effects, making it an attractive option for patients with this disease.

Lutetium-177 PSMA therapy in india

Latest Therapy for best treatment of Prostate Cancer in India

Lu177 Therapy is a true breakthrough in prostate cancer treatment. It has proved effective in not only reducing the size of tumours but also in stopping the cancerous cells from multiplying. This therapy has successfully been able to achieve long-term remission, thus helping patients lead a better quality of life post treatment.

This therapy has proved itself to be a useful therapy for management of metastatic prostate cancer for which other types of treatments have failed.

Who is eligible for Lutetium-177 Therapy?

There are very few hospitals in India that offer such an progressive cancer treatment option like this. Patients suffering from advanced and metastatic prostate cancer are eligible for this therapy that actually combines therapy with diagnostics.

Before your Lu177 therapy gets started, a diagnostic scan called Ga-68 PSMA PET CTwill be performed to ensure that the therapy’s radiation accurately targets the right areas during treatment.

Lutetium-177 therapy is exclusively used for males suffering from prostate cancer that has originated in the prostate area and for whom other lines of treatment have failed to offer relief.

How does Lutetium-177 Therapy work?

PSMA is a kind of protein found on the membrane of prostate cells, and is believed to have several cellular functions. The cancerous prostate tumors create extremely high levels of lutetium as compared to epithelium cells of the prostate. It is almost 1000 times higher than a normal cell of the prostate.

You also need to note that if prostate cancer has spread to other body organs then this PSMA can be found in those areas as well.

During the Lu177 PSMA therapy, lutetium which is a radiation-based treatment, uses a molecule for attaching itself to the PSMA receptors positioned on the cancer cells. The Lu177 releases beta radiation that efficiently damages cancer cells and, over a period of time, it destroys them.

How does Lutetium-177 Therapy work?

When do the best doctors for prostate cancer in India recommend Lu177 PSMA Therapy?

Lutetium-177 PSMA Therapy is a quite precise therapy used for management of metastatic Prostate Cancer or when your Prostate Cancer would no longer be responsive to other kinds of treatment.

The therapy is recommended to patients diagnosed to have Advanced Castration-resistant Metastatic Prostate Cancer with indication of tumour increasing in size. Cancer progression may be seen in the form of:

  • Pain aggravation or other deteriorating symptoms due to the disease
  • Rise in Serum PSA levels
  • Increase in the size or quantity of the metastatic lesions on Ga68 PSMA scans or CT/MRI

Your doctor will not suggest you Lu177 PSMA Therapy in case of -Your doctor will not suggest you Lu177 PSMA Therapy in case of –

  • Extreme haematological compromise
  • Poor function of the kidneys

Treatment Duration for Lu177 PSMA Therapy

As far as treatment schedule of Lu177 Therapy is concerned, patients majorly undergo 3 to 4 treatment cycles at a gap of 8 to 12 weeks. The number of therapy cycles and the interval between 2 cycles varies from one individual to another. It also depends upon individual’s response to previous cycles.

The average dosage of Lu PSMA Therapy given varies in the range of 5.5 – 11GBq for each treatment cycle and the doses are primarily based on pretreatment dose assessment. Ionizing radiation dose that gets absorbed by a human body is precisely measured, calculated and assessed by a treating doctor while planning the therapy.

On the day of treatment, your doctor will admit you as an inpatient in the hospital in a Specialised High Dose Radioisotope Therapy Unit for the purpose of monitoring and also radiation protection.

Outcome of Lu177 PSMA Therapy in India

The outcome of Lu177 PSMA therapy depends upon several factors like – nature of tumour of your prostate cancer, the preliminary Gleason Score, the extent to which disease has spread and also the responses to prior therapies you have undergone.

In general, more than 70%-80%of patients are known to have shown a reduction in PSA levels and also shrinkage of tumours post Lu177 PSMA therapy in India. Not only this, you will be glad to know that almost all patients show a reduction in pain and improvement in overall health as soon as they receive the 2nd dose of this therapy.

Lutetium-177 (Lu-177) PSMA (Prostate-Specific Membrane Antigen) therapy is the newest development in the treatment of prostate cancer. This therapy is highly precise, as Lu-177 elements get fixed directly to the PSMA receptor that is present at the surface of prostate cancer cells, thus causing damage to their DNA directly by emitting a minor amount of Beta-radiation.

Damage to nearby tissues and related side effects are reduced by targeting the cancer cells directly with radiation. According to a clinical study, people who were given PSMA therapy along with standard prostate cancer treatment lived longer as compared to those who received only standard treatment. The study also showed improvement in disease progression amongst people who received Lu-177 PSMA therapy.

Outcome of Lu177 PSMA Therapy in India

Cost of Lutetium or Lu177 PSMA Therapy in India

The best prostate cancer hospital in India is not only one of the world’s most advanced centers for Nuclear Medicine but also offers the lowest cost for most advanced treatments like Lu177 Therapy. It is the most cost effective centre in India offering this therapy at half of the cost that you may end up paying in countries like Malaysia or Thailand, and 1/3rd of the cost you would pay if you travel to Germany or any other developed nation offering this treatment. Contact us today to know the cost of lutetium-177 PSMA Therapy.

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