Introduction

Prostate cancer is amongst one of the most common cancers diagnosed in men. According to some of the best doctors for prostate cancer in India, most of the prostate cancers get diagnosed at an early stage, there is still a significant portion that has local or distant metastases.

Over the years, we have seen how prostate cancer patients have struggled to find a suitable treatment for their medical condition. For example – Patients having mCRPC (Metastatic Castrate Resistant Prostate Cancer) suffer from an advanced stage of prostate cancer that quite often proves to be fatal to their life.

However, now there is an emerging breakthrough treatment option called – Actinium 225 PSMA Therapy. This has become a preferred option for patients suffering from advanced mCRPC, and who have undergone treatment with current existing forms of therapy but failed to get relief.

Best doctors for prostate cancer treatment in India have found that patients with advanced and severely pre-treated mCRPC have been showing good response to Actinium 225 PSMA therapy.

How Does Actinium-225 PSMA Therapy Work?

• Hospitals make use of an alpha-emitting radioisotope for treating prostate cancer. These are short-range & high energy radiations which make the therapy highly effective in precisely targeting and destroying prostate cancer cells.
• In Targeted Therapies, the Actinium 225 isotope gets attached to a specific targeted molecule, just like an antibody. It then locks itself on a specific antigen on the cancerous cells.
• Once the decaying of isotope happens, it starts emitting high-energy alpha particles which then kill the prostate cancer cells by causing irreversible damage, like shattering DNA cells.
• The best part is that the healthy cells in surrounding areas remain unharmed by this entire process.

Actinium-225: One of the rarest drugs!

• There is a very limited availability of this rarest radioisotope – Actinium 225, making it difficult for healthcare institutes to procure it easily or for that matter the usage too is very well thought and planned.
• It is interesting to learn that Actinium 225 is being considered as a new weapon in the fight against prostate cancer.
• The production of this radioisotope is so rare that the annual global production is reported to be less than a grain of sand!

Who is eligible for Ac-225 PSMA Therapy?

• Patients with progressive stages of prostate cancer are known to benefit from Actinium-225 PSMA Therapy. In certain cases, Actinium-225 PSMA Therapy has proven to be more effective than Lutetium-177 PSMA Therapy.
• Thus, patients who are tired of trying all other modules of prostate cancer treatment, can consult our expert doctors about the possible advantages of Actinium-225 PSMA Therapy.
• We also advise you to discuss in detail with your doctor regarding the possible risks as well as benefits of this therapy before your treatment commences.

What are the tests required before undergoing Actinium-225 Therapy?

• Before you undergo the Actinium 225 therapy, your doctor will prefer and suggest you undergo thorough screening. This screening would help your doctor understand the exact stage of your prostate cancer.
• Some basic blood investigations of your marrow function, renal functioning, and PSA levels are normally suggested. Besides this, PSMA PET/CT test will also be required so that your doctor can do baseline staging and complete assessment of tumour PSMA ligand avidness.
• You will also be required to give detailed history of all your previous therapies like surgical intervention, chemotherapy, radiotherapy, radioligand or targeted therapy.

What happens during the treatment with Actinium-225 PSMA Therapy?

Actinium 225 PSMA therapy treatment normally takes around 1 to 1.5 hours and can easily be done on OPD basis. The therapy involves insertion of an intravenous line, and the Actinium-225 PSMA is injected slowly through IV. You need not worry about any complications or possible side effects during the infusion as this is done by our expert team after detailed planning and customized treatment plan for your condition.

Outcome of Actinium-225 PSMA Therapy in India

• Based on a recent study conducted by doctors on 17 patients who underwent Actinium-225 PSMA therapy, it was found that14 out of 17 patients experienced a PSA reduction of ≥90% which is truly remarkable. None of the patients in this study had any adverse side effects or were needed to stop treatment with Actinium-225 PSMA.
• These initial studies prove the potential of Actinium 225 PSMA Therapy in treating advanced prostate cancer patients. Therefore, this therapy is truly a new ray of hope for prostate cancer patients.
• In order to get best results, PSMA-therapy with Actinium-225 is done in several sessions. This elevates the exposure time of radiation to cancer cells and, thus, enhances the effectiveness of this therapy.
• The number of sessions will be decided by your doctor on the basis of your medical condition and the outcome of follow-up evaluations.

Booking Your PSMA Therapy with Actinium-225 at the best prostate cancer hospital in India

The Super Speciality Care team helps hundreds of patients every year to undergo PSMA treatment in India and defeat the deadly disease of prostate cancer without much hassle.

• We will be happy to assist you right from the moment of choosing the best hospital for Actinium-225 therapy in India till returning to your native country. Our team will first collect all your clinical details and medical history for the doctor’s opinion and also assist you in getting a visa letter as soon as possible.
• Once the treatment plan is provided to you and you decide to travel to India, we will fix your prior appointment with the treating doctor here.
• You will get complimentary airport pick up on the day of arrival in India. Once you reach the hospital, you will get assistance from your case coordinator who will handle all your queries and requirements end-to-end.

In conclusion, Actinium-225 (Ac-225) PSMA therapy is a new, promising treatment for prostate cancer that is currently only available in India. This therapy uses a radioactive isotope of actinium to target and destroy cancer cells, while sparing healthy tissue. Ac-225 PSMA therapy has been shown to be effective in treating both early and advanced stages of prostate cancer, with minimal side effects. This new therapy offers hope for men with prostate cancer who have few other treatment options available to them. Contact us to know the cost of Actinium (Ac225) PSMA Therapy in India.